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tumors

Thursday 4 March 2004

solid tumors, human tumors, solid tumor

Classification

- epithelial tumors

  • benign epithelial tumors
  • malignant epithelial tumors (Carcinomas )

- mesenchymal tumors

  • benign mesenchymal tumors
  • malignant mesenchymal tumors (Sarcomas )

- blastemal tumors (embryonic tumors or Blastomas )
- melanocytic tumors
- germ cell tumors
- cerebral tumors
- hematopietic tumors and lymphoid tumors

  • leukemias
  • lymphoid neoplasms (lymphomas )

Diagnosis

- tumoral moprhology
- tumoral appearance

According to tumoral architecture - Examples

- lobular tumors (lobular pattern)
- trabecular tumors (trabecular pattern)

According to cell appearance

- fusiform cell tumors
- round cell tumors

- signet ring cell tumors
- clear cell tumors

Localization

- cutaneous tumors
- digestive tumors
- renal tumors
- salivary gland tumors
- soft tissue tumors
- osseous tumors
- nervous tumors
- placental tumors

Features

- tumoral vascularization (tumor vascularization )
- tumoral phenotype
- fetal tumors and neonatal tumors
- tissular specificity of tumors
- tumoral cells
- tumoral stroma

Miscellaneous

- neonatal tumors
- cystic tumors

Items

- immunochemistry
- cytogenetics
- molecular biology

  • fusion proteins
  • allelotype (LOH loci )
  • inactivated genes
  • activated genes
  • underexpressed genes
  • overexpressed genes

Links

- Solid tumors at AGCOH (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
- CancerIndex
- cancer-genetics.org
- AFIP Atlas of Tumor Pathology, Series III

References

- An update in molecular diagnostics of solid tumors. Dacic S. Arch Pathol Lab Med. 2011 May;135(5):535-6. PMID: 21526951

- Albertson DG, Collins C, McCormick F, Gray JW. Chromosome aberrations in solid tumors. Nat Genet. 2003 Aug;34(4):369-76. PMID: 12923544

- Mitelman F, Johansson B, Mertens F. Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nat Genet. 2004 Apr;36(4):331-4. PMID: 15054488

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