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giant cell fibroblastoma

Friday 21 May 2004

Definition: Phenotypic variant of dermatofibrosarcoma protuberans sharing the same COL1A1/PDGFB fusion gene.

Cytogenetics

- t(17;22)(q22;q13) creating COL1A1/PDGFB fusion protein

Molecular biology

- COL1A1/PDGFB fusion protein by t(17;22)(q22;q13) (COL1A1 at 17q22 and PDGFB at 22q13

See also

- fusion genes
- fusion proteins