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ovarian fibroma

Tuesday 8 June 2004

A Definition: Ovarian fibroma is a common ovarian sex cord-stromal tumor. Ovarian fibroma has dense benign spindle cells. It is associated with Meigs syndrome (ovarian fibroma, ascites, right pleural effusion), and Gorlin syndrome (basal cell nevus syndrome - basal cell carcinomas, odontogenic keratocyst, PTCH gene, autosomal dominant). Links - [Ovarian fibroma->http://www.webpathology.com/image.asp?n=22&Case=533] at WebPathology Synopsis - usually unilateral. - hard, solid, grey-white masses. - fibroblasts (fibroblastic tumor) ([WebPathology->http://www.webpathology.com/image.asp?n=24&Case=533]) - The fusiform cells have small, spindle-shaped nuclei lacking atypia or mitotic activity. Associations - In 40% of cases, these tumors are associated with hydrothorax usually on the right side and ascites (Meigs syndrome). Variants - ovarian cellular fibroma See also - fibromas - ovarian tumors -* ovarian stromal tumors

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