Humpath.com - Human pathology

Home > E. Pathology by systems > Skin > nevus lipomatosus superficialis

nevus lipomatosus superficialis

Thursday 12 January 2006

naevus lipomatosus superficialis ; nevus lipomatosus cutaneous superficialis, Hoffmann-Zurhelle

WKP PO

Definition: Nevus lipomatosus superficialis (NLS) is a rare benign cutaneous hamartoma characterized by papules and nodules usually in the pelvic and sacral areas, with ectopic mature adipose tissue reaching the superficial dermis.

Images

- nevus lipomatosus superficialis

Synopsis

- Rare, benign cutaneous hamartoma
- @<@ 2y
- Multiple soft, papules, nodules, plaques
- Buttocks, upper thigh, lower back
- Normal epidermis
- Superficial dermis with lobules of adipocytes

Associations

- multiple folliculosebaceous cystic hamartomas (FCH) (15649197)
- dermoid cysts (15649197)
- perifollicular fibrosis (14721781)
- basal cell carcinoma (12786865)
- cavernous hemangioma (3074101)

Cytogenetics

- 2p24 deletion (17223884)

See also

- Skin

References

- Cardot-Leccia N, Italiano A, Monteil MC, Basc E, Perrin C, Pedeutour F. Naevus lipomatosus superficialis: a case report with a 2p24 deletion. Br J Dermatol. 2007 Feb;156(2):380-1. PMID: 17223884

Portfolio