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Holt-Oram syndrome

Wednesday 24 September 2003


- Mutations in TBX5, a T-box-containing transcription factor, cause cardiac and limb malformations in individuals with Holt-Oram syndrome (HOS).


- Packham EA, David Brook J. Interaction makes the heart grow stronger. Trends Mol Med. 2003 Oct;9(10):407-9. PMID: 14557051