Disease localization

Articles

• nodal Kawasaki disease
  9 January 2006

  Definition: lymph node lesions in Kawasaki disease.
  Synopsis
  multiple foci of necrosis (#7149090#)
  fibrin thrombi within the microvasculature (#7149090#)
  Most lymphadenopathy is non-specific, caused by sinus expansion and paracortical zone enlargement, but there are also necrotic lesions of various sizes that can be surmised to result from ischaemic changes in some LNs.
  Necrotic foci start to develop immediately below the capsule, and are accompanied by fibrin thrombi in the small (...)

• renal SLE
  24 October 2005

  renal systemic lupus erythematosus

• renal von Hippel-Lindau disease
  4 March 2005

  References
  Solomon D, Schwartz A. Renal pathology in von Hippel-Lindau disease. Hum Pathol. 1988 Sep;19(9):1072-9. PMID: #3417291#

• CMV vasculitis
  27 January 2005

  Synopsis
  leukocytoclastic vasculitis
  typical intranuclear CMV inclusions in enlarged endothelial cells associated
  intravascular thrombus formation
  vascular luminal narrowing
  References
  Curtis JL, Egbert BM. Cutaneous cytomegalovirus vasculitis: an unusual clinical presentation of a common opportunistic pathogen. Hum Pathol. 1982 Dec;13(12):1138-41. PMID: #6293957#

• nodular glomerulosclerosis
  12 May 2004

  Syn. Kimmelstiel-Wilson lesion
  Images
  diabetic nephropathy https://twitter.com/dozing_dog/status/744723125393203201 https://twitter.com/Gleason4plus5/status/750784164904001536
  See also
  diabetes
  renal diseases / nephropathies
  glomerulosclerosis nodular glomerulosclerosis Kimmelstiel-Wilson lesion
  References
  Ng DP, Krolewski AS. Molecular genetic approaches for studying the etiology of diabetic nephropathy. Curr Mol Med. 2005 Aug;5(5):509-25. PMID: (...)

• renal Goodpasture syndrome
  12 May 2004

  Synopsis
  increased cell proliferation often starts focally
  no thickening of glomerular basal membrane
  crescent formation (cell proliferation in Bowman space)
  capillary collapse
  IF: Positive IgG with linear (smooth) pattern

• Pseudomonas pneumonia
  7 September 2005

  Synopsis
  paucicellular coagulative confluent bronchopneumonia with perivascular bacillary infiltration
  cellular pneumonia without evidence of perivascular organisms
  References
  Bonifacio SL, Kitterman JA, Ursell PC. Pseudomonas pneumonia in infants: an autopsy study. Hum Pathol. 2003 Sep;34(9):929-38. PMID: #14562290#

• pulmonary sarcoidosis
  14 September 2005

  Images
  Sarcoidosis in The Yale Rosen Collection of Pulmonary Pathology on Flickr
  https://twitter.com/ARTinPathology/status/558099263943884802
  Definition: Pulmonary localization is by far the most common in individuals with sarcoidosis. About 90% of patients have an abnormal chest X-ray at some time during the course of their disease. Overall, about 50% develop permanent pulmonary abnormalities, and 5 to 15% have progressive fibrosis of the lung parenchyma.
  Sarcoidosis of the lung is (...)

• esophageal GVHD
  25 February 2005

  oesophageal GVHD

• CMV oesophagitis
  27 January 2005

  Synopsis
  CMV inclusions
  inflammtory granulation tissue aggregates of macrophages (#9042804#) perivascular distribution of macrophages in granulation tissue
  exudates
  esophageal ulcers
  patchy aggregates of macrophages in exudates
  References
  Greenson JK. Macrophage aggregates in cytomegalovirus esophagitis. Hum Pathol. 1997 Mar;28(3):375-8. PMID: #9042804#

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