Protein family

Articles

• cryptochromes
  28 February 2006

  CRYs

• SPTs
  27 February 2006

  spectrins

• RAFs
  12 February 2006

  Members RAF1 RAF2
  References
  Yuryev A, Wennogle LP. The RAF family: an expanding network of post-translational controls and protein-protein interactions. Cell Res. 1998 Jun;8(2):81-98. PMID: #9669024#

• ELKs
  12 February 2006

  ELKs are members of the ETSs oncogene superfamily.
  Members ELK1 ELK2 ELK3 ELK4

• protein tyrosine phosphatases
  14 February 2006

  Cytoplasmic protein tyrosine phosphatases, PTPs

• DVLs
  14 February 2006

  dishevelled proteins (DVLs)

• CELSRs
  14 February 2006

  epidermal grow factor like proteins, homolgs of drosophila flamingo

• NATs
  17 February 2006

  Members NAT1 NAT2
  The human N-acetyltransferase genes NAT1 and NAT2 encode two phase-II enzymes that metabolize various drugs and carcinogens. Functional variability at these genes has been associated with adverse drug reactions and cancer susceptibility.
  Pathology
  Mutations in NAT2 leading to the so-called slow-acetylation phenotype reach high frequencies worldwide, which questions the significance of altered acetylation in human adaptation.
  NAT2*5B haplotype, which seems to (...)

• FANCs
  3 March 2006

  Seven Fanconi anemia-associated proteins (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG and FANCL) form a nuclear Fanconi anemia core complex that activates the monoubiquitination of FANCD2, targeting FANCD2 to BRCA1-containing nuclear foci.
  Cells from individuals with Fanconi anemia of complementation groups D1 and J (FA-D1 and FA-J) have normal FANCD2 ubiquitination.
  Members
  Fanconi anemia complementation group genes (FANCs) - 12 complementations groups Locus Gene MIM Location FANCA (...)

• MAP3Ks
  12 February 2006

  MEKKs

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