Protein family

Articles

• NOTCHs
  7 March 2004

  Notchs

• steroid hormone receptors
  8 February 2006

  SHRs

• LGALs
  4 April 2005

  galectins

• MSXs
  26 May 2004

  Vertebrate Msx genes are unlinked, homeobox-containing genes that bear homology to the Drosophila muscle segment homeobox gene.
  Members MSX1 MSX2
  MSXs genes are expressed at multiple sites of tissue-tissue interactions during vertebrate embryonic development.
  Inductive interactions mediated by the MSXs genes are essential for normal craniofacial, limb and ectodermal organ morphogenesis, and are also essential to survival in mice, as manifested by the phenotypic abnormalities shown (...)

• formins
  27 November 2003

  Formins are a large family of multi-domain polypeptides that form homodimers. The highly conserved formin homology 2 (FH2) domain and its neighboring formin homology 1 (FH1) domain, which are surrounded by regulatory domains, cooperate in rapidly assembling profilin-actin into long filaments while remaining continuously associated with the fast-growing barbed end.
  Recent biochemical, biophysical, theoretical and structural studies have concluded that diverse formins are mechanistically (...)

• COLs
  4 June 2003

  Collagen

• TERFs
  26 January 2005

  Members TERF1 TERF2

• DNA glycosylases
  27 May 2005

  DNA glycosylases remove the aberrant base from the DNA backbone by hydrolyzing the N-glycosidic bond (monofunctional DNA glycosylase), or further catalyze the incision of a resulting abasic site (bifunctional DNA glycosylase).
  Functions
  Reactive oxygen species from endogenous and environmental sources induce oxidative damage to DNA, and hence pose an enormous threat to the genetic integrity of cells.
  Base excision repair (BER) protects against damage to DNA from reactive oxygen species, (...)

• CCLs
  4 February 2005

  CC chemokines, beta-chemokines
  Definition: CCLs are beta-chemokines, a family of chemokines containing 2 adjacent cysteines (CC).
  Members CCL1 CCL2 CCL3 CCL4 CCL5 CCL6 CCL7 CCL8 CCL9 CCL10 CCL11 CCL12 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28
  See also
  chemokines alpha-chemokines (CXCs ) (characterized by a single amino acid separating the first 2 (...)

• RABs
  29 October 2003

  RAS-related RAB proteins, ras-related superfamily of GTPases, Rab GTPases, Rab proteins

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