Translocation-associated tumors

Articles

• salivary mucoepidermoid carcinoma
  8 March 2004

  salivary gland mucoepidermoid carcinoma PO WKP WP
  Definition: The mucoepidermoid carcinoma is the most common malignant neoplasm observed in the major and minor salivary glands.
  Mucoepidermoid carcinoma is the most common adult salivary malignancy. It histologically is non-encapsulated and shows three cell types - squamous, mucous and intermediate, and may show prominent oncocytic change. It is associated with t(11;19) fusing MECT1 and MAML2 (MAML2-MECT1 fusion gene).
  Images
  Small (...)

• clear cell sarcoma of the kidney
  14 July 2004, by JA

  CCSK, renal clear cell sarcoma; bone-metastasizing renal tumour of childhood AGCOH PathConsult eMedicine
  Digital slides
  Case 66 (HPC:66) : Clear cell sarcoma of the kidney (CCSK)
  Definition: Clear cell sarcoma of the kidney (CCSK) is a malignant renal tumor of childhood with a propensity to metastasize to bone and other organs. CCSK is linked to internal tandem duplications (ITDs) of the BCOR gene.
  This tumor may also recur many years after its initial diagnosis. The average age (...)

• pancreatic solid pseudopapillary tumor
  12 November 2003

  PSPPT; solid-pseudopapillary tumor of the pancreas, Frantz tumor, Frantz’s tumor; solid pseudopapillary tumor of the pancreas; ICD-O codes Solid pseudopapillary neoplasm 8452/1, Solid pseudopapillary carcinoma 8452/3; pancreatic solid pseudopapillary tumor; pancreatic solid and pseudopapillary tumor; Solid-pseudopapillary neoplasm of the pancreas PathConsult
  Definition: Solid pseudopapillary neoplasms of the pancreas are rare pancreatic tumors with mostly benign behavior, affecting (...)

• diffuse type of giant cell tumor of tendon sheath
  18 February 2004

  pigmented villonodular synovitis; pigmented villonodular tenosynovitis; tenosynovial giant cell tumor, diffuse type; diffuse type of giant-cell tumor of the tendon sheath (GCTTS); tenosynovial giant cell tumor-diffuse type; formerly called pigmented villonodular synovitis (PVNS) when occurs near a joint; giant cell tumor of tendon sheath, diffuse type
  /WP/
  Definition: Diffuse giant cell tumor of tendon sheath (pigmented villonodular synovitis) is an extra-articular, destructive (...)

• myxoid liposarcoma
  1 November 2007

  Definition: Myxoid liposarcoma displays variably aggressive behavior and responds poorly to available systemic therapies.
  Images
  myxoid liposarcoma
  https://twitter.com/histiocytosisX/status/748157284644196352
  https://twitter.com/a_sleeping_dog/status/773402045911007232
  https://twitter.com/JMGardnerMD/status/737075990086590466
  https://twitter.com/DanglisFotiosMD/status/734976870110900225
  https://twitter.com/solcosao/status/706608037868404736
  FISH FUS rearrangement (...)

• lipoblastoma
  7 October 2005

  Fetal Lipoma, Infantile Lipoma, Embryonic Lipoma
  Definition: Lipoblastoma is a rare benign tumor that arises from embryonic adipose tissue and usually occurs in young children. It is a lobulated, localized (lipoblastoma) or diffuse (lipoblastomatosis) tumor, resembling fetal adipose tissue.
  Images
  Lipoblastoma
  https://twitter.com/DrBastaki/status/767703201810374656
  https://twitter.com/kabeerkshah/status/711948424606670849
  https://twitter.com/GSomersPath/status/875061142745436161 (...)

• mucoepidermoid carcinoma
  14 June 2006

  pulmonary mucoepidermoid carcinoma; mucoepidermoid carcinoma of the bronchi;
  Digital cases
  HPC:95: pulmonary mucoepidermoid carcinoma.
  JRC:6447 : pulmonary mucoepidermoid carcinoma.
  JRC:19401 : pulmonary mucoepidermoid carcinoma.
  Images
  Mucoepidermoid carcinoma
  https://twitter.com/chioseasi/status/715338200479301633
  https://twitter.com/Helena_Path/status/853996400216035330
  https://twitter.com/bunn_belinda/status/867813656968519680 (...)

• myxoid/round cell liposarcoma
  7 October 2005

  myxoid liposarcoma and round cell liposarcoma group; MRC-LPS
  Definition: Myxoid and round cell liposarcoma accounts for about 30% to 35% of all liposarcomas and, even if still classified by the World Health Organization (WHO) as 2 distinct subtypes, share both clinical and morphologic features.
  See also :
  myxoid liposarcoma
  round cell liposarcoma
  Lesions combining both patterns are frequent and wide agreement exists in considering round cell liposarcoma as the high grade counterpart (...)

• alveolar rhabdomyosarcoma
  25 November 2003

  Images
  Alveolar rhabdomyosarcoma.
  https://twitter.com/histiocytosisX/status/699599913013923840
  https://twitter.com/seattlequinns/status/855202143564742656
  ARMS : focal desmin w/ diffuse myogenin in A-RMS (PCR + PAX3-FOXO1)
  https://twitter.com/histiocytosisX/status/730475540524699649
  Compact ARMS : Alveolar rhabdomyosarcoma may lack alveolar spaces. Solid nodules uniform round cells,fibrous septa. DIFFUSE myogenin.
  https://twitter.com/JMGardnerMD/status/856870953011347456 (...)

• hemosiderotic fibrolipomatous tumor
  19 May 2008

  haemosiderotic fibrohistiocytic lipomatous tumour (HFHLL); HFLT
  Definition: Hemosiderotic fibrolipomatous tumor is an extremely rare, nonencapsulated, fatty lesion with a consistent histologic appearance that was originally considered reactive in nature.
  Images
  https://twitter.com/histiocytosisX/status/723617790456913921
  Cytogenetics
  reciprocal translocation between chromosomes 1 and 10, with a further rearrangement involving this derivative chromosome 1 and chromosome 3 (#18406878#) (...)

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