Translocation-associated tumors

Articles

• clear cell sarcoma of the kidney
  14 July 2004, by JA

  CCSK, renal clear cell sarcoma; bone-metastasizing renal tumour of childhood AGCOH PathConsult eMedicine
  Digital slides
  Case 66 (HPC:66) : Clear cell sarcoma of the kidney (CCSK)
  Definition: Clear cell sarcoma of the kidney (CCSK) is a malignant renal tumor of childhood with a propensity to metastasize to bone and other organs. CCSK is linked to internal tandem duplications (ITDs) of the BCOR gene.
  This tumor may also recur many years after its initial diagnosis. The average age (...)

• pancreatic solid pseudopapillary tumor
  12 November 2003

  PSPPT; solid-pseudopapillary tumor of the pancreas, Frantz tumor, Frantz’s tumor; solid pseudopapillary tumor of the pancreas; ICD-O codes Solid pseudopapillary neoplasm 8452/1, Solid pseudopapillary carcinoma 8452/3; pancreatic solid pseudopapillary tumor; pancreatic solid and pseudopapillary tumor; Solid-pseudopapillary neoplasm of the pancreas PathConsult
  Definition: Solid pseudopapillary neoplasms of the pancreas are rare pancreatic tumors with mostly benign behavior, affecting (...)

• myxoid/round cell liposarcoma
  7 October 2005

  myxoid liposarcoma and round cell liposarcoma group; MRC-LPS
  Definition: Myxoid and round cell liposarcoma accounts for about 30% to 35% of all liposarcomas and, even if still classified by the World Health Organization (WHO) as 2 distinct subtypes, share both clinical and morphologic features.
  See also :
  myxoid liposarcoma
  round cell liposarcoma
  Lesions combining both patterns are frequent and wide agreement exists in considering round cell liposarcoma as the high grade counterpart (...)

• myxoid liposarcoma
  1 November 2007

  PO
  Definition: Myxoid liposarcoma displays variably aggressive behavior and responds poorly to available systemic therapies.
  Images
  myxoid liposarcoma https://twitter.com/histiocytosisX/status/748157284644196352 https://twitter.com/a_sleeping_dog/status/773402045911007232 https://twitter.com/JMGardnerMD/status/737075990086590466 https://twitter.com/DanglisFotiosMD/status/734976870110900225 https://twitter.com/solcosao/status/706608037868404736
  FISH FUS rearrangement (...)

• salivary mucoepidermoid carcinoma
  8 March 2004

  salivary gland mucoepidermoid carcinoma PO WKP WP
  Definition: The mucoepidermoid carcinoma is the most common malignant neoplasm observed in the major and minor salivary glands.
  Mucoepidermoid carcinoma is the most common adult salivary malignancy. It histologically is non-encapsulated and shows three cell types - squamous, mucous and intermediate, and may show prominent oncocytic change. It is associated with t(11;19) fusing MECT1 and MAML2 (MAML2-MECT1 fusion gene).
  Images
  Small (...)

• pleomorphic adenoma
  8 March 2004

  Mixed tumor of salivary glands; salivary pleomorphic adenoma; salivary benign mixed tumor; BMT; pleomorphic adenomas; benign mixed tumor WKPD PO WP
  Definition: Pleomorphic adenoma is a benign neoplastic tumor of the salivary glands. As the name implies, these epithelial tumors are characterized by great histologie diversity; but despite increased cellularity, they are essentially benign lesions.
  Pleomorphic adenoma is the most common type of salivary gland tumor and the most common (...)

• mucoepidermoid carcinoma
  14 June 2006

  pulmonary mucoepidermoid carcinoma; mucoepidermoid carcinoma of the bronchi;
  Digital cases
  HPC:95: pulmonary mucoepidermoid carcinoma.
  JRC:6447 : pulmonary mucoepidermoid carcinoma.
  JRC:19401 : pulmonary mucoepidermoid carcinoma.
  Images
  Mucoepidermoid carcinoma
  https://twitter.com/chioseasi/status/715338200479301633
  https://twitter.com/Helena_Path/status/853996400216035330
  https://twitter.com/bunn_belinda/status/867813656968519680 (...)

• lipoblastoma
  7 October 2005

  Fetal Lipoma, Infantile Lipoma, Embryonic Lipoma
  Definition: Lipoblastoma is a rare benign tumor that arises from embryonic adipose tissue and usually occurs in young children. It is a lobulated, localized (lipoblastoma) or diffuse (lipoblastomatosis) tumor, resembling fetal adipose tissue.
  Images
  Lipoblastoma
  https://twitter.com/DrBastaki/status/767703201810374656
  https://twitter.com/kabeerkshah/status/711948424606670849
  https://twitter.com/GSomersPath/status/875061142745436161 (...)

• NUT midline carcinoma
  5 May 2009

  NUT-associated carcinoma NMC
  Definition: NUT midline carcinoma (NMC) is a high-grade malignancy that is defined by rearrangement of the nuclear protein in testis (NUT) gene on chromosome 15q14.
  NMCs are morphologically indistinguishable from other poorly differentiated carcinomas, and the diagnosis is usually made currently by fluorescence in situ hybridization (FISH).
  Images
  NUT midline carcinoma
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746135/figure/Fig1/ (...)

• giant cell angiofibroma
  11 October 2005

  Definition: Giant cell angiofibroma is a phenotypic variant of solitary fibrous tumor (SFT).
  Giant cell angiofibroma seems most often to arise in the head and neck region (predominantly orbit) of adults and which, with the passage of time.
  It may well prove to be a variant of solitary fibrous tumour characterized by prominent multinucleate giant cells and lipofibromatosis.
  It is a rare tumour occurring predominantly in the hands or feet of infants and young children.
  it shows a high (...)

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