Translocation-associated tumors

Articles

• myxoid/round cell liposarcoma
  7 October 2005

  myxoid liposarcoma and round cell liposarcoma group; MRC-LPS
  Definition: Myxoid and round cell liposarcoma accounts for about 30% to 35% of all liposarcomas and, even if still classified by the World Health Organization (WHO) as 2 distinct subtypes, share both clinical and morphologic features.
  See also :
  myxoid liposarcoma
  round cell liposarcoma
  Lesions combining both patterns are frequent and wide agreement exists in considering round cell liposarcoma as the high grade counterpart (...)

• pleomorphic adenoma
  8 March 2004

  Mixed tumor of salivary glands; salivary pleomorphic adenoma; salivary benign mixed tumor; BMT; pleomorphic adenomas; benign mixed tumor WKPD PO WP
  Definition: Pleomorphic adenoma is a benign neoplastic tumor of the salivary glands. As the name implies, these epithelial tumors are characterized by great histologie diversity; but despite increased cellularity, they are essentially benign lesions.
  Pleomorphic adenoma is the most common type of salivary gland tumor and the most common (...)

• clear cell sarcoma of the kidney
  14 July 2004, by JA

  CCSK, renal clear cell sarcoma; bone-metastasizing renal tumour of childhood AGCOH PathConsult eMedicine
  Digital slides
  Case 66 (HPC:66) : Clear cell sarcoma of the kidney (CCSK)
  Definition: Clear cell sarcoma of the kidney (CCSK) is a malignant renal tumor of childhood with a propensity to metastasize to bone and other organs. CCSK is linked to internal tandem duplications (ITDs) of the BCOR gene.
  This tumor may also recur many years after its initial diagnosis. The average age (...)

• mucoepidermoid carcinoma
  14 June 2006

  pulmonary mucoepidermoid carcinoma; mucoepidermoid carcinoma of the bronchi;
  Digital cases
  HPC:95: pulmonary mucoepidermoid carcinoma.
  JRC:6447 : pulmonary mucoepidermoid carcinoma.
  JRC:19401 : pulmonary mucoepidermoid carcinoma.
  Images
  Mucoepidermoid carcinoma
  https://twitter.com/chioseasi/status/715338200479301633
  https://twitter.com/Helena_Path/status/853996400216035330
  https://twitter.com/bunn_belinda/status/867813656968519680 (...)

• lipoblastoma
  7 October 2005

  Fetal Lipoma, Infantile Lipoma, Embryonic Lipoma
  Definition: Lipoblastoma is a rare benign tumor that arises from embryonic adipose tissue and usually occurs in young children. It is a lobulated, localized (lipoblastoma) or diffuse (lipoblastomatosis) tumor, resembling fetal adipose tissue.
  Images
  Lipoblastoma
  https://twitter.com/DrBastaki/status/767703201810374656
  https://twitter.com/kabeerkshah/status/711948424606670849
  https://twitter.com/GSomersPath/status/875061142745436161 (...)

• aggressive angiomyxoma
  7 February 2006

  AAMs, ’aggressive’ angiomyxoma; deep aggressive angiomyxoma
  Definition: Aggressive angiomyxoma (AA) is a distinctive, locally aggressive, fibromyxoid tumor of the pelvic and genital soft tissues.
  Digital case
  JRC:1443 : Aggresive angiomyxoma of pelvic soft tissues.
  JRC:14570 : Aggresive angiomyxoma of peritoneum (ischiorectal fossa).
  Images
  Deep (agressive) angiomyxoma. Young women vulvar tumor
  https://twitter.com/luishcruzc/status/758685476341415936 (...)

• giant cell angiofibroma
  11 October 2005

  Definition: Giant cell angiofibroma is a phenotypic variant of solitary fibrous tumor (SFT).
  Giant cell angiofibroma seems most often to arise in the head and neck region (predominantly orbit) of adults and which, with the passage of time.
  It may well prove to be a variant of solitary fibrous tumour characterized by prominent multinucleate giant cells and lipofibromatosis.
  It is a rare tumour occurring predominantly in the hands or feet of infants and young children.
  it shows a high (...)

• salivary mucoepidermoid carcinoma
  8 March 2004

  salivary gland mucoepidermoid carcinoma PO WKP WP
  Definition: The mucoepidermoid carcinoma is the most common malignant neoplasm observed in the major and minor salivary glands.
  Mucoepidermoid carcinoma is the most common adult salivary malignancy. It histologically is non-encapsulated and shows three cell types - squamous, mucous and intermediate, and may show prominent oncocytic change. It is associated with t(11;19) fusing MECT1 and MAML2 (MAML2-MECT1 fusion gene).
  Images
  Small (...)

• HMGA2-associated inflammatory myofibroblastic tumor
  3 February 2010

  HMGIC-associated inflammatory myofibroblastic tumor

• ALK/CARS-associated inflammatory myofibroblastic tumor
  3 February 2010

  References
  Identification of CARS-ALK fusion in primary and metastatic lesions of an inflammatory myofibroblastic tumor. Debelenko LV, Arthur DC, Pack SD, Helman LJ, Schrump DS, Tsokos M. Lab Invest. 2003 Sep;83(9):1255-65. PMID: #13679433#

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