cellular cycle
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Cellular functions
Articles
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cell cycle
13 July 2003 -
cellular aging
7 March 2004Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
A number of cell functions decline progressively with age.
Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...) -
phagocytosis
23 April 2004WKP
Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
Phagocytosis involves three distinct but interrelated steps:
(1) recognition and attachment of the particle to be ingested by the leukocyte;
(2) its engulfment, with subsequent (...) -
cellular differentiation
13 July 2003cytodifferentiation
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endocytosis
16 September 2003endocytic pathway, endocytic trafficking
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chemosensation
25 November 2003References
Prasad BC, Reed RR. Chemosensation: molecular mechanisms in worms and mammals. Trends Genet. 1999 Apr;15(4):150-3. PMID: #10203825# -
mitoses
13 July 2003mitosis
Images
in a glandular epithelium
https://twitter.com/BeynonMD/status/740787261046919169
in epidermis
https://twitter.com/doctormisti/status/
numerous atypical mitoses
https://twitter.com/smlungpathguy/status/743442537763971073
Pathology
abnormal mitosis / abnormal mitoses
quantitative variations
no mitosis
increased mitoses
low mitotic activity / inconspicuous mitoses
moderate mitotic activity / frequent mitoses
high mitotic activity / numerous mitoses (...) -
extracellular matrix remodeling
11 July 2003References
Stamenkovic I. Extracellular matrix remodelling: the role of matrix metalloproteinases. J Pathol. 2003 Jul;200(4):448-64. PMID: #12845612# -
cellular interactions
10 July 2003Types
immune-cell interactions
Pathology of cellular interactions
References
Friedl P, Storim J. Diversity in immune-cell interactions: states and functions of the immunological synapse. Trends Cell Biol. 2004 Oct;14(10):557-67. PMID: #15450978# -
genomic stability
13 July 2003A fundamental axiom of genetic inheritance is a requirement for exceptional genetic stability over many generations of cells and organisms. However, cells have to contend with both intracellular and extracellular environments that constantly challenge the chemical stability of the genome.
Additionally, although normal metabolic transactions of DNA such as replication, recombination and repair are generally highly accurate, there are limits to the fidelity of these processes, so genomic (...)