Cellular functions

Articles

• cellular aging
  7 March 2004

  Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
  A number of cell functions decline progressively with age.
  Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...)

• phagocytosis
  23 April 2004

  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis (literally, cell-eating) is the process by which cells ingest large objects, such as cells which have undergone apoptosis, bacteria, or viruses. The membrane folds around the (...)

• internalization
  15 September 2003
• cell-cycle arrest
  13 July 2003
• cell survival
  10 November 2003

  cellular survival

• retraction
  14 February 2006

  Cells utilize actin filaments to produce protrusive and contractile arrays that cooperate to drive cell motility.
  The generation of the two arrays and the coupling between them result from the unique properties of the lamellipodium, a protrusive leaflet of cytoplasm at the cell edge.
  From the lamellipodium into the lamella behind, there is a transition from a fast retrograde flow of actin polymer driven by polymerization to a slow flow driven by the interaction of anti-parallel arrays of (...)

• cellular trafficking
  16 October 2003

  Types
  vesicular trafficking
  Pathology
  anomalies of vesicular trafficking, anomalies of endosomal trafficking Griscelli disease
  anomalies of cellular trafficking hereditary spastic paraplegia
  References
  Stein M, Wandinger-Ness A, Roitbak T. Altered trafficking and epithelial cell polarity in disease. Trends Cell Biol. 2002 Aug;12(8):374-81. PMID: #12191914#
  Karcher RL, Deacon SW, Gelfand VI. Motor-cargo interactions: the key to transport specificity. Trends Cell Biol. 2002 (...)

• cytokinesis
  15 September 2003

  Process by which the daugther cells separate from each other at the end of the cellular division
  Cytokinesis follows nuclear division and generates two distinct daughter cells, each replete with a full complement of the genome and cytoplasmic organelles.
  Completion of cell division during cytokinesis requires temporally and spatially regulated communication from the microtubule cytoskeleton to the actin cytoskeleton and the cell membrane.
  Exit from the cytokinetic phase of the cell cycle (...)

• telomere shortening
  19 July 2003

  telomere erosion, short telomeres

• vesicle trafficking
  13 July 2003

  vesicular transport of proteins, vesicular trafficking, intra-cellular-membrane transport

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