Cellular functions

Articles

• phagocytosis
  23 April 2004

  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis (literally, cell-eating) is the process by which cells ingest large objects, such as cells which have undergone apoptosis, bacteria, or viruses. The membrane folds around the (...)

• cellular aging
  7 March 2004

  Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
  A number of cell functions decline progressively with age.
  Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...)

• cell cycle
  13 July 2003

  cellular cycle

• endocytosis
  16 September 2003

  endocytic pathway, endocytic trafficking

• cellular invasion
  29 October 2003

  tumor cell invasion, cancer cell invasion

• focal contacts
  12 February 2006

  See also
  focal contacts
  cell motility
  cell migration
  FAK (focal adhesion kinase)
  References
  Schlaepfer DD, Mitra SK. Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev. 2004 Feb;14(1):92-101. PMID: #15108811#
  Petit V, Thiery JP. Focal adhesions: structure and dynamics. Biol Cell. 2000;92(7):477-94. PMID: #11229600#
  Wehrle-Haller B, Imhof B. The inner lives of focal adhesions. Trends Cell Biol. 2002 Aug;12(8):382-9. PMID: (...)

• cytoskeletal functions
  5 February 2006

  References
  Gruenheid S, Finlay BB. Microbial pathogenesis and cytoskeletal function. Nature. 2003 Apr 17;422(6933):775-81. PMID: #12700772#

• cytoxicity
  12 February 2006

  See also
  lymphocyte-mediated cytotoxicity
  lytic granules (cytotoxic granules)
  CD8+ cytotoxic lymphocytes
  cytotoxic granule-mediated apoptosis
  References
  Hong W. Cytotoxic T lymphocyte exocytosis: bring on the SNAREs! Trends Cell Biol. 2005 Dec;15(12):644-50. PMID: #16260137#
  Raja SM, Metkar SS, Froelich CJ. Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism. Curr Opin Immunol. 2003 Oct;15(5):528-32. PMID: #14499261#
  de Saint Basile G, Fischer A. The role (...)

• retraction
  14 February 2006

  Cells utilize actin filaments to produce protrusive and contractile arrays that cooperate to drive cell motility.
  The generation of the two arrays and the coupling between them result from the unique properties of the lamellipodium, a protrusive leaflet of cytoplasm at the cell edge.
  From the lamellipodium into the lamella behind, there is a transition from a fast retrograde flow of actin polymer driven by polymerization to a slow flow driven by the interaction of anti-parallel arrays of (...)

• cytotoxicity
  8 March 2007

  Videos
  T-cell mediated cytotoxicity

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