Molecular function

Articles

• nucleotide excision repair
  19 November 2003

  NER pathway, NER system

• DNA damage
  15 September 2003

  DNA lesions, DNA damages WKP
  Definition: All cells can sustain DNA damage from various sources that are conveniently classified as either endogenous or exogenous in origin.
  See also :
  naturally occurring DNA damage
  DNA damage by reactive oxygen species
  In human cells, both normal metabolic activities and environmental factors such as UV light can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day.
  Many of these lesions cause (...)

• oxidative phosphorylation
  30 September 2003

  electron transport system, oxydative phosphorylation, electron transport reaction in mitochondria, OXPHOS system, respiratory chain

• base excision repair
  20 November 2003

  Definition: Base excision repair (BER) protects against damage to DNA from reactive oxygen species, methylation, deamination, hydroxylation and other by-products of cellular metabolism.
  The survival of organism depends on the accurate transmission of genetic information from one cell to its daughters. Such faithful transmission requires not only extreme accuracy in replication of DNA and precision in chromosome distribution, but also the ability to survive spontaneous and induced DNA (...)

• low-copy repeats
  14 October 2003

  LCRs

• fatty acid omega oxidation
  25 October 2004

  While the main route of fatty acid metabolism is through beta-oxidation, some minor metabolic pathways such as omega oxidation also contribute to the metabolism of fatty acids and other molecules.
  Omega oxidation occurs in the endoplasmic reticulum rather than the mitochondria, the site of beta-oxidation.
  The omega carbon in a fatty acid is the carbon furthest in the alkyl chain from the carboxylic acid. In the omega oxidation pathway, this carbon is progressively oxidized first to an (...)

• sterol
  7 October 2003

  sterols

• RNA repair
  2 July 2004

  References
  Mansfield SG, Chao H, Walsh CE. RNA repair using spliceosome-mediated RNA trans-splicing. Trends Mol Med. 2004 Jun;10(6):263-8. PMID: #15177190#

• gene expression
  16 October 2003

  protein expression

• transcription
  16 July 2003

  gene-expression

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