Tumoral subtypes

Articles

• uterine endometrioid adenocarcinoma, FIGO grade 1
  25 November 2010

  type 1 endometrial carcinoma
  Definition: Relatively indolent tumors that arise in background of endometrial hyperplasia.
  According to one definition, when endometrial glands show a confluent pattern occupying at least 2x2 mm focus, the diagnosis of adenocarcinoma can be made. Smaller foci are labeled "complex endometrial hyperplasia".
  The diagnosis of endometrioid adenocarcinoma can also be made if there is extensive papillary pattern or infiltrative glands with desmoplastic response. (...)

• thymoma type B2
  7 December 2012

  Definition: Type B2 thymoma is composed of clusters of neoplastic epithelial cells in a background of abundant immature T-cells. The epithelial cell density is higher than that seen in type B1 thymoma or the normal thymus. Foci of medullary differentiation may or may not be seen. It makes up 25% to 30% of all thymomas.
  This image shows thick fibrous septa dividing the tumor into lobules.
  Type B2 thymoma is usually seen in adults in their 5th or 6th decade of life. Almost 55% of patients (...)

• plexiform schwannoma
  14 September 2005

  plexiform cellular schwannoma

• non-ossifying fibroma
  8 September 2004

  Fibrous cortical defect, cortical defect, nonossifying fibroma; non-ossifying fibroma; benign fibrous histiocytoma if mass-forming and involving the medullary cavity. NOF
  Definition: Non-ossifying fibroma is a benign, lytic lesion of fibrous origin most often observed in the metaphyseal region of the long bones in children and adolescents.
  Images
  Non-ossifying fibroma / NOF
  https://twitter.com/Maryross86/status/860657829203648512 (...)

• bilateral cystic neuroblastoma
  10 November 2009

  References
  Life-Threatening Bilateral Adrenal Cystic Neuroblastoma in an Infant. Avanzini S, Conte M, Granata C, Zamorani EM, Sementa AR, Garaventa A, Buffa P, Sorrentino S. J Pediatr Hematol Oncol. 2009 Oct 31. PMID: #19887960#
  Liver transplant in an infant with bilateral cystic neuroblastoma complicated by hepatic metastases and life-threatening consumption coagulopathy. Haberal M, Ozcay F, Sevmis S, Karakayali H, Moray G, Torgay A, Coskun M, Demirhan B, Sarialioglu F, Arslan G. (...)

• germ cell tumor with malignant transformation
  2 October 2007

  germ cell tumor with sarcomatous components

• microscopic medullary thyroid carcinoma
  9 November 2010

  microscopic MCT; medullary thyroid microcarcinomas

• giant cell-rich osteosarcoma
  25 November 2010

  giant cell rich osteoblastic osteosarcoma

• anaplastic astrocytoma
  7 October 2005

  Anaplastic astrocytoma (AA, WHO grade III) is, second to Glioblastoma, the most common and most malignant type of adult CNS tumour.
  Cytogenetics
  In anaplastic astrocytomas, chromosome gains or losses are frequent:
  trisomy 7 (the most frequent)
  loss of chromosome 10
  loss of chromosome 22
  loss of 9p,
  loss of 13q.
  Other abnormalities, less frequently described are: gains of chromosomes 1q, 11q, 19, 20, and Xq.
  Molecular biology
  loss of both wild-type copies of genes in the (...)

• nodular ganglioneuroblastoma
  12 March 2010

  Digital slides
  Case 26 : nodular ganglioneuroblastoma
  Definition: Ganglioneuroblastoma, nodular (GNBn) is a rare subtype of the family of neuroblastic tumors (neuroblastoma, ganglioneuroblastoma, and ganglioneuroma) that are classified in the unfavorable histology group according to the International Neuroblastoma Pathology Classification (INPC - Shimada system).
  Tumors of this subtype have been considered to represent a prototypic example of biologically and clinically nonaggressive (...)

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