G. Tumoral pathology

• PIK3CA-related overgrowth spectrum disorder
  16 March

  Cancer-Associated PIK3CA Mutations in Overgrowth Disorders
  See also : PIK3CA
  Definition : PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found in benign overgrowth syndromes, collectively known as PIK3CA-related overgrowth spectrum (PROS).
  As in cancer, PIK3CA mutations in PROS arise postzygotically, but unlike in cancer, these mutations arise during embryonic development, with their timing and location critically influencing the resulting (...)

• RET-rearranged tumors
  16 March

  RET-driven cancers
  Types (Examples)
  RET-rearranged carcinomas RET-rearranged thyroid carcinomas RET-rearranged pulmonary adenocarcinoma RET-rearranged colorectal adenocarcinoma
  RET-rearranged fusiform cell tumors

• plasmacytoid tumors
  13 March

  Examples
  plasmacytic tumors
  plasmacytoid melanoma
  plasmacytoid urothelial carcinoma https://twitter.com/Rus13Co/status/1105737198928826368
  See also
  plasmacytoid appearance

• inflammatory background
  12 March

  Examples
  inflammatory myofibroblastic tumor Examples : https://twitter.com/daniel_berney/status/1095299013002301444
  myxoinflammatory fibroblastic sarcoma https://twitter.com/mufster82/status/1105207586511638529
  inflammatory stroma in carcinomas
  See also
  architectural patterns

• small cell lung carcinomas
  9 March

  Examples
  pulmonary small cell lung carcinoma
  high grade neuroendocrine carcinoma
  See also
  carcinomas
  diagnosis of carcinomas
  small cell tumors

• granulomatous stroma
  18 February

  Images
  Seminoma with florid granulomatous reaction including necrosis and granulomatous vasculitis https://twitter.com/yro854/status/1097186140111687680
  See also
  granulomatous inflammation / granulomatous infiltration
  tumoral stroma

• fusiform cell tumors with inflammatory background
  12 February

  Variants
  inflammatory myofibroblastic tumor Examples : https://twitter.com/daniel_berney/status/1095299013002301444
  myxoinflammatory fibroblastic sarcoma https://twitter.com/mufster82/status/1105207586511638529
  See also
  fusiform cell tumors
  inflammatory background / inflammatory stroma

• hyalinized vessels in tumors
  9 February

  Examples
  PLEOMORPHIC HYALINIZING ANGIECTATIC TUMOR (PHAT) https://twitter.com/mariaramir/status/723662298389352452 https://twitter.com/DrSampyRoy/status/733023871725494274 https://twitter.com/DrAlodaini/status/950091320625958913 https://twitter.com/SteveBillingsMD/status/905427241361969152

• highly vascularized tumors
  9 February

  Etiology
  vascular tumors
  telangiectatic osteosarcoma
  Examples
  PLEOMORPHIC HYALINIZING ANGIECTATIC TUMOR (PHAT) https://twitter.com/mariaramir/status/723662298389352452 https://twitter.com/DrSampyRoy/status/733023871725494274 https://twitter.com/DrAlodaini/status/950091320625958913 https://twitter.com/SteveBillingsMD/status/905427241361969152

• myxedematous stroma
  9 February

  Examples
  Proliferative fasciitis https://twitter.com/histiocytosisX/status/726137886693806081 https://twitter.com/VishwasParekh/status/701774294997716992 https://twitter.com/feaselp811/status/733792267266330624
  See also
  tumoral stroma myxoid stroma edematous stroma

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