G. Tumoral pathology

• nontranslocation-associated sarcomas
  27 September 2005

  References
  Montgomery E, Argani P, Hicks JL, DeMarzo AM, Meeker AK. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. Am J Pathol. 2004 May;164(5):1523-9. PMID: #15111298#

• translocation-associated sarcomas
  27 September 2005

  Exemples
  alveolar rhabdomyosarcoma
  t(2;13)(q35;q14) (PAX3-FOXO1A)
  t(1;13)(p36;q14) (PAX7-FOXO1A)
  myxoid liposarcoma
  t(12;16)(q13;p11) (FUS-DDIT3)
  t(12;22)(q13;q12) (EWSR1-DDIT3)
  congenital fibrosarcoma and cellualr mesoblastic nephroma
  t(12;15)(p13;q26) (ETV6-NTRK3)
  dermatofibrosarcoma protuberans/giant cell fibroblastoma:
  t(17;22)(q22;q13) (COL1A1-PDGFB)
  alveolar soft part sarcoma
  t(X;17)(p11;q25) (TFE3-ASPL)
  synovial sarcoma
  t(X;18)((p11.2;q11.2) (SS1B-SSX1; (...)

• ossifying tumors
  27 September 2005

  bone-forming tumors, osteogenic tumors

• stromal hyalinization
  27 September 2005

  Types
  osteosarcomas
  hyalinizing soft tissue tumors sclerosing epithelioid fibrosarcoma pleomorphic hyalinizing angiectatic tumor ossifying fibromyxoid tumor of soft tissue hyalinizing spindle cell tumor with giant rosettes or hyalinizing variant of low-grade fibromyxoid sarcoma sclerosing rhabdomyosarcoma
  hyalinizing epithelial tumors hyalinizing trabecular adenoma of the thyroid hyalinizing clear-cell carcinoma of the salivary gland (HCCC)
  others hyalinizing Spitz nevus (...)

• ossifying fibromyxoid tumor of soft tissue
  27 September 2005

  ossifying fibromyxoid tumor of soft parts; ossifying fibromyxoid tumor; OFMT. Ent. Enzinger, 1959. Nom. Enzinger, 1959.
  Definition: The ossifying fibromyxoid tumor of soft parts (OFMT) is an uncommon soft tissue neoplasm of uncertain lineage.
  It is now appreciated that a small but significant subset of these lesions may give rise to metastases, often in association with atypical histological features such as increased cellularity and mitotic activity.
  Images (...)

• proximal-type epithelioid sarcoma
  27 September 2005

  Definition: Proximal-type epithelioid sarcoma is a recently described soft-tissue tumor that is distinguished from conventional-type epithelioid sarcoma by a far more aggressive clinical course, frequent location in the proximal anatomic regions, and variable rhabdoid morphology.
  Because of their rarity and peculiar morphology, proximal-type epithelioid sarcomas frequently pose serious diagnostic dilemmas, being easily misdiagnosed as a variety of other malignant neoplasms.
  Synopsis (...)

• plexiform schwannoma
  14 September 2005

  plexiform cellular schwannoma

• oncocytic tumors
  9 September 2005

  oncocytomas
  Digital case
  JRC:1175 : Hurthle cell adenoma
  Localization
  salivary oncocytoma
  thyroid oncocytoma (Hurthle cell adenoma)
  renal oncocytoma renal oncocytomatosis

• tumoral metabolism
  6 September 2005

  References
  Stubbs M, Bashford CL, Griffiths JR. Understanding the tumor metabolic phenotype in the genomic era. Curr Mol Med. 2003 Feb;3(1):49-59. PMID: #12558074#

• tubular tumors
  26 August 2005

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