Spleen

• splenic nodules
  27 December 2019

  splenic nodule
  Examples
  Sclerozing Angiomatoid Nodular Transformation ; SANT of the spleen https://twitter.com/NigarAKhurram/status/1151145348078997504 https://twitter.com/SibaElHussein/status/1209166039742730241
  splenic tumors
  See also
  nodules
  splenic anomalies

• sclerosing angiomatoid nodular transformation
  17 July 2019

  Sclerozing Angiomatoid Nodular Transformation ; SANT
  Examples
  Sclerozing Angiomatoid Nodular Transformation ; SANT of the spleen https://twitter.com/NigarAKhurram/status/1151145348078997504 https://twitter.com/SibaElHussein/status/1209166039742730241
  Synopsis
  Prominent nodular architecture, with a dense peri-nodular fibrosis.
  The nodules are composed of vascular spaces with no atypical features,admixed with fibroblasts and scattered inflammatory cells
  See also
  splenic vascular (...)

• splenic diseases
  6 June 2018

  PO
  See also : splenic anomalies

• splenic hemosiderosis
  2 January 2018

  Images
  splenic hemosiderosis https://twitter.com/JCGarcesPath/status/947518397738377217
  See also
  hemosiderosis

• splenic sclerosing angiomatoid nodular transformation
  4 December 2017

  Sclerosing angiomatoid nodular transformation of the spleen; SANT
  Predisposition
  Maffucci syndrome Some patients are diagnosed with Maffucci syndrome along with sclerosing angiomatoid nodular transformation (SANT) of the spleen. Maffucci syndrome is a congenital, non-hereditary mesodermal dysplasia characterized by multiple enchondromas and hemangiomas. The presence of visceral vascular lesions in this syndrome is exceedingly rare.
  Open references
  Sclerosing angiomatoid nodular (...)

• splenic Gaucher disease
  11 May 2017

  Images
  Splenic Gaucher disease https://twitter.com/seattlequinns/status/860539487595540480 https://twitter.com/rositadeolivop1/status/882009573355290625
  See also
  splenic diseases
  Gaucher disease

• splenic amyloidosis
  19 May 2013

  spleen amyloidosis
  PO
  Synopsis
  Macroscopy
  firm consistency
  waxy consistency
  possible sago spleen
  possible lardaceous spleen
  splenomegaly
  diffuse splenic infiltration
  possible localized splenic nodules
  rare splenic rupture
  Microscopy
  splenic deposition of pink amorphous material deposition of pink amorphous material limited either to germinal follicles (sago spleen) deposition of pink amorphous material along splenic sinusoids deposition of pink amorphous material in (...)

• splenic infectious mononucleosis
  18 May 2013

  PO
  Microscopy
  expansion of red pulp immunoblastic proliferation in red pulp Immunoblasts may have strikingly atypical morphology, resemble Reed-Sternberg cells immunoblastic infiltration of subintima of intratrabecular veins Immunoblasts are positive for B and T cell markers, EBV by in situ hybridization, variable CD30
  red pulp hemophagocytosis
  Differential diagnosis
  Hodgkin lymphoma
  splenic localization of leukemia
  splenic (...)

• spleen in hereditary spherocytosis
  18 May 2013

  PO
  Digital slides
  UI:742 : spleen in hereditary spherocytosis.
  Macroscopy
  Microscopy
  marked congestion of red pulp
  empty appearance of sinuses (actually contain ghost red blood cells)
  * may have prominent endothelial lined sinuses
  red pulp hemosiderin deposition
  red pulp erythrophagocytosis
  Videos
  Hereditary spherocytosis by Washington Deceit
  See also
  erythrocytic (...)

• spleen in hemolytic anemia
  18 May 2013

  Types of hemolytic anemia
  congenital hemolytic anemia hereditary spherocytosis sickle cell anemia
  acquired hemolytic anemia deposition of immune complexes on red blood cell membranes bacterial hemolysins plasma lipid abnormalities parasites
  immune hemolytic anemia brucellosis Hodgkin lymphoma leukemia sarcoidosis SLE (lupus) tuberculosis
  Microscopy
  splenic congestion in cords and sinuses
  splenic hemosiderin deposition
  splenicextramedullary hematopoiesis (...)

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