A. Molecular pathology

• energy
  20 April

  WKP
  Definition : Energy is a physical quantity measuring the capacity of a system to modify a state, to produce a work producing a movement, heat or an electromagnetic radiation.
  In physics, energy is the quantitative property that is transferred to a body or to a physical system, recognizable in the performance of work and in the form of heat and light.
  Energy is a conserved quantity. The law of conservation of energy states that energy can be converted in form, but not created or (...)

• Precambrian
  3 April

  precambrian WKP
  Definition : The Precambrian ( Cryptozoic ) is the earliest part of Earth history, set before the current Phanerozoic Eon.
  The Precambrian is so named because it preceded the Cambrian, the first period of the Phanerozoic Eon, which is named after Cambria, the Latinised name for Wales, where rocks from this age were first studied.
  The Precambrian accounts for 88% of the Earth’s geologic (...)

• organic chemistry
  3 April

  WKP
  Definition : Organic chemistry is a branch of chemistry that studies the structure, properties and reactions of organic compounds, which contain carbon-carbon covalent bonds. Study of structure determines their structural formula.
  The study of organic reactions includes the chemical synthesis of natural products , drugs , and polymers , and study of individual organic molecules in the laboratory and via theoretical (in silico) (...)

• organic transformation
  3 April

  The IUPAC nomenclature for organic transformations
  The IUPAC Nomenclature for Transformations is a methodology for naming a chemical reaction. Traditionally a chemical reaction especially in organic chemistry is named after its inventor, the so-called name reaction.
  https://en.wikipedia.org/wiki/IUPAC_nomenclature_for_organic_transformations
  See also
  organic chemistry

• chemical reaction
  3 April

  WKP
  Definition : A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another.
  Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the nuclei (no change to the elements present), and can often be described by a chemical equation.
  Nuclear chemistry is a sub-discipline of chemistry that involves the chemical (...)

• catalysis
  3 April

  WKP
  Catalysis is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst.
  Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate.
  Catalysts generally react with one or more reactants to form intermediates that subsequently give the final (...)

• PI3K
  27 November 2021

  Phosphoinositide 3-kinase
  See also : PI3Ks

• BCL10
  14 October 2021

  Images
  pancreatoblastoma https://twitter.com/medannabel/status/1448629962102108160

• cathepsin-K
  7 January 2021

  CTSK WKP PO
  Definition : Cathepsin K, abbreviated CTSK, is an enzyme that in humans is encoded by the CTSK gene. The protein encoded by this gene is a lysosomal cysteine protease involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is expressed predominantly in osteoclasts.
  Pathology
  Germline mutations cause sclerosing osteochondrodysplasia pycnodysostosis, a rare autosomal recessive skeletal dysplasia characterized by (...)

• MUC5B
  13 November 2020

  Pathology
  MUC5B anomalies in pulmonary fibrosis / peripheral lobular fibrosis
  Open references
  Pathogenesis of idiopathic pulmonary fibrosis: review of recent findings.2014. PMID: #25165568#
  Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. 2013. PMID: #23268535#
  The epithelium in idiopathic pulmonary fibrosis: breaking the barrier. 2014. PMID: #24454287#
  Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin. 2016. (...)

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