Humpath.com - Human pathology

Home > E. Pathology by systems > Digestive system > Colon and rectum > eosinophilic colitis

eosinophilic colitis

Friday 3 October 2003

Primary Colonic Eosinophilia

Definition: Eosinophilic colitis is an inflammatory condition characterized by infiltration of the colonic wall by eosinophils with submucosal oedema.

Involvement of caecum, appendix, ascending colon and the omentum by the inflammatory process could mimic a right iliac fossa neoplasm. Eosinophilic colitis is rare and could mimic a right iliac neoplasm if it is right-sided.

Etiology

- allergic colitis
- parasitic colitis

  • Enterobius vermicularis colitis
  • Strongyloides stercoralis colitis

- drug-induced eosinophilic colitis

- hypereosinophilic syndrome (3432177)
- idiopathic eosinophilic colitis

Associations

- allogeneic bone marrow transplantation (12894856)
- Tolosa-Hunt syndrome (12858845)

Variants

- neonatal eosinophilic colitis (7062205)

Differential diagnosis

- 39% to 57% of eosinophilic granulocytes in Crohn’s disease (12812315)
- 3.3% to 9% of eosinophilic granulocytes in ulcerative colitis (12812315)

Variants

- neonatal eosinophilic colitis

Associations

- perianal disease

Paywall Refrerences

- Primary Colonic Eosinophilia and Eosinophilic Colitis in Adults. Turner KO, Sinkre RA, Neumann WL, Genta RM. Am J Surg Pathol. 2016 Oct 27. PMID: 27792062

- Eosinophilic colitis presenting as a right iliac fossa mass—a case report. Badmos KB, Sabageh D, Ojo OS, Balogun OS. West Afr J Med. 2008 Jul;27(3):175-7. PMID: 19256325

- Persic M, Stimac T, Stimac D, Kovac D. Eosinophilic colitis: a rare entity. J Pediatr Gastroenterol Nutr 2001 Mar;32(3):325-6. PMID: 11345185