- Human pathology

Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > Cancer cytogenetics > CGH anomalies > CGH gains > 17q gain

17q gain

Tuesday 1 May 2007

Gain of chromosome 17 is the most prevalent genetic abnormality identified in neuroblastoma (NB) and distal 17q gain has prognostic significance in NB.

Candidate genes

- WSB1 at 17q11.1 (16804916)

See also

- array-based comparative genomic hybridization (A-CGH or aCGH)
- gene expression analysis
- gene copy number changes (GCNC)
- prognosis genes
- chromosome 17


- Chen QR, Bilke S, Wei JS, Greer BT, Steinberg SM, Westermann F, Schwab M, Khan J. Increased WSB1 copy number correlates with its over-expression which associates with increased survival in neuroblastoma. Genes Chromosomes Cancer. 2006 Sep;45(9):856-62. PMID: 16804916