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11q23 deletion

Wednesday 19 September 2007

Tumors

- mantle cell lymphoma (16382446)
- chronic lymphocytic leukemia (15672409, 16418492)

References

- Guikema JE, de Boer-Bergsma RW, Akkermans K, Schuuring E, Kluin PM. H2AX is not affected in mantle cell lymphoma with 11q23 deletion. Genes Chromosomes Cancer. 2006 Apr;45(4):426-7. PMID: 16382446

- Kröber A, Bloehdorn J, Hafner S, Bühler A, Seiler T, Kienle D, Winkler D, Bangerter M, Schlenk RF, Benner A, Lichter P, Döhner H, Stilgenbauer S. Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia. J Clin Oncol. 2006 Feb 20;24(6):969-75. PMID: 16418492

- Auer RL, Starczynski J, McElwaine S, Bertoni F, Newland AC, Fegan CD, Cotter FE. Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia. Genes Chromosomes Cancer. 2005 May;43(1):1-10. PMID: 15672409