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CD30+ lymphoproliferative disorders

Tuesday 4 December 2007

Types

- classical Hodgkin lymphoma (cHL)
- ALK+ anaplastic large cell lymphoma (ALCL)
- ALK+ anaplastic large cell lymphoma (ALCL)
- primary cutaneous anaplastic large cell lymphoma (ALCL)
- CD30+ diffuse large B-cell lymphoma (CD30+ DLBCL)
- lymphomatoid papulosis

c-Jun

CD30 lymphomas are characterized by common patterns of c-Jun expression and activation suggesting a potential role of c-Jun in the pathogenesis of these tumors.

References

- Drakos E, Leventaki V, Schlette EJ, Jones D, Lin P, Medeiros LJ, Rassidakis GZ. c-Jun expression and activation are restricted to CD30+ lymphoproliferative disorders. Am J Surg Pathol. 2007 Mar;31(3):447-53. PMID: 17325487