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portal hypertension

Wednesday 18 June 2008

Definition: Abnormal increase of resistance to blood flow within the hepatic portal system, frequently seen in liver cirrhosis and conditions with obstruction of thportal vein.

Etiology

- cirrhosis
- Cruveilhier-Baumgarten syndrome
- hepatic arterioportal fistula

- PKDs

- cardiac and vascular conditions

  • hepatic vein thrombosis

- autoimmune conditions

  • primary sclerosing cholangitis

- tumors

  • pancreatic adenocarcinomas

- trauma, mechanical and physical conditions

  • hepatic portal vein obstruction
  • hepatic vein occlusion
  • Schistosoma japonicum
  • Schistosoma mansoni

Complications

- haemorrhoids
- hepatorenal syndrome
- gastrointestinal bleeding
- esophageal varices
- pulmonary hypertension


- DDB