portal hypertension

Definition: Abnormal increase of resistance to blood flow within the hepatic portal system, frequently seen in liver cirrhosis and conditions with obstruction of thportal vein.

Etiology

 cirrhosis
 Cruveilhier-Baumgarten syndrome
 hepatic arterioportal fistula

 PKDs

• autosomal dominant polycystic kidney disease (hepatic ADPKD)
• autosomal recessive polycystic kidney disease (Hepatic ARPKD)

 cardiac and vascular conditions

• hepatic vein thrombosis

 autoimmune conditions

• primary sclerosing cholangitis

 tumors

• pancreatic adenocarcinomas

 trauma, mechanical and physical conditions

• hepatic portal vein obstruction
• hepatic vein occlusion
• Schistosoma japonicum
• Schistosoma mansoni

Complications

 haemorrhoids
 hepatorenal syndrome
 gastrointestinal bleeding
 esophageal varices
 pulmonary hypertension