Humpath.com - Human pathology

Home > E. Pathology by systems > Locomotory system > Bones > fibrous tumors of bone

fibrous tumors of bone

Tuesday 8 December 2009

Digital cases

- Case 100 (HPC:100) : Fibrous dysplasia of bones

Definition: Benign and malignant fibrous tumors of bone are some of the most common tumors encountered by the orthopedic surgeon.

Types

- reactive or post-traumatic tumors of bone

  • periosteal "desmoid" tumors
  • non-ossifying fibroma
    • fibrous cortical defect
    • fibrous metaphyseal defect
    • benign fibrous histiocytoma

- benign fibrous tumors of bones

  • fibrous dysplasia (fibro-osseous dysplasia, fibro-osseous lesion)
  • osteofibrous dysplasia (differentiated adamantinoma)
  • desmoplastic fibroma of bone
  • desmoid fibromatosis of bone
  • liposclerosing myxofibrous tumor

- malignant fibrous bone tumors

  • malignant fibrous histiocytoma
  • fibrosarcoma of bone
  • adamantinoma of long bones

Fibrous dysplasia, fibrous cortical defect, non-ossifying fibroma, benign fibrous histiocytoma and osteofibrous dysplasia are benign tumors best treated conservatively or by intralesional/marginal excision.

Desmoplastic fibromas are locally aggressive and require a wide margin for surgical cure.

Malignant fibrous histiocytoma and fibrosarcoma of bone are malignant bone tumors and must be treated with wide/radical margins and for malignant fibrous histiocytoma adjunctive chemotherapy.

See also

-  fibroblastic tumors of bone
- fibrosarcoma of bone