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periosteal desmoid tumor

Wednesday 2 June 2010

PERIOSTEAL ‘DESMOID’ TUMORS

Definition: The periosteal desmoid tumor is a fairly common fibrous lesion that most commonly affects boys in the first two decades of life.

Localization

The periosteal desmoid tumor arises on the posteromedial aspect of the lower metaphysis of the femur in the region of the attachment of the adductor magnus and the medial head of the gastrocnemius.

It is characteristic in location and does not warrant a biopsy.

Imaging

Imaging studies reveal erosion of the cortex, with a sclerotic base.

Microscopy

Microscopically, periosteal desmoids are composed of vascularized and disorganized dense collagenous tissue with uniform unremarkable fibroblasts and admixed reactive immature bone formation.

A scalloped periosteal defect with a sclerotic base in the posteromedial metaphysis of the femur is the characteristic radiographic appearance of a periosteal desmoid tumor, a benign lesion, possibly post-traumatic.

Synopsis

- Abundant collagen production by poorly organized but unremarkable fibroblasts.
- A scalloped periosteal defect with a sclerotic base in the posteromedial metaphysis of the femur.
- benign lesion
- possibly post-traumatic.
- dense fibrous tissue
- Abundant collagen production by poorly organized but unremarkable fibroblasts.

Etiology

- The lesion almost certainly occurs as the result of previous trauma.

See also

- fibrous tumors of bone