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Tuesday 11 October 2011

Human-papillomaviruses (HPV) type 16 is a causative agent in an increasing subset of oropharyngeal squamous cell carcinomas (OPSCCs). These tumors have distinct oncogenic mechanisms and a more favorable prognosis than tobacco-induced OPSCCs.

See also

- HPVs


- A predictive transcriptomic signature of oropharyngeal cancer according to HPV16 status exclusively. Mirghani H, Ugolin N, Ory C, Lefèvre M, Baulande S, Hofman P, St Guily JL, Chevillard S, Lacave R. Oral Oncol. 2014 Aug 21. pii: S1368-8375(14)00229-2. doi : 10.1016/j.oraloncology.2014.07.019 PMID: 25156715

- Herdman MT, Pett MR, Roberts I, et al. Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants. Carcinogenesis 2006;27:2341–53.