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prostatic malakoplakia

Sunday 22 January 2012

prostate malakoplakia


- May involve prostate, usually associated with bladder disease
- Ages 47+
- Represents a peculiar form of tissue reaction to bacterial infection
- Usually periductal, may resemble carcinoma on ultrasound, may actually coexist with carcinoma
- Prostate enlarged on clinical examination
- The prostatic glands are replaced by sheets of histiocytes, lymphocytes, and plasma cells.
- Targetoid Michelis-Gutmann bodies are seen.

Differential diagnosis

- nodular histiocytic prostatitis


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