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oncocytic prostate acinar adenocarcinoma

Sunday 12 February 2012

Oncocytic variant

Prostatic adenocarcinoma rarely is composed of large cells with granular
eosinophilic cytoplasm.

Tumour cells have round to ovoid hyperchromatic nuclei, and are strongly positive for PSA.

Numerous mitochondria are seen on ultrastructural examination. A high Gleason grade, elevated serum PSA and metastasis of similar morphology have been reported.