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juvenile pernicious anemia

Sunday 4 March 2012

Juvenile Forms of Pernicious Anemia

Juvenile pernicious anemia is rare and has three distinct forms:
- One occurs in late childhood and adolescence and appears to resemble the adult form ofthe disease in allrespects except the age of patient presentation.
- So-called “true”juvenile pernicious anemia results from the failure of the parietal cells to produce intrinsic factor. The stomach is histologically normal and acid is produced by the parietal cells. The cause of the failure to produce intrinsic factor is not understood.
- The third type results from failed absorption ofthe vitamin B12–intrinsic factor complex.

See also

- autoimmune gastritis (pernicious anemia)