- Human pathology

Home > E. Pathology by systems > Digestive system > Stomach > gastric sarcoidosis

gastric sarcoidosis

Sunday 4 March 2012

Gastric sarcoidosis is unusual and can only be diagnosed with conīŦdence when gastric granulomas occur in the setting ofdocumented sarcoid in other organs,such as in the liver, lungs, or hilar lymph nodes, and in the absence of microorganisms in the granulomas.

Asymptomatic gastric involvement affects approximately 10% of sarcoid patients.

Symptomatic patients present with gastric ulcers, hemorrhage, pyloric stricture, and gastric outlet obstruction.

Endoscopic changes range from a distal gastritis with or without nodularity to ulceration and pyloric stenosis.

The histologic features ofthe granulomas resemble those seen elsewhere in the body.

They tend to associate with fewer lymphocytes and plasma cells than one sees in patients with Crohn disease, unless the patient has coexisting chronic gastritis.

See also

- granulomatous gastritis