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Home > E. Pathology by systems > Digestive system > Colon and rectum > colorectal lymphoid polyp

colorectal lymphoid polyp

Tuesday 20 March 2012

Large intestinal lymphoid polyps and focal lymphoid hyperplasia most commonly arise in the rectum.

They may reflecta reactive change to a prior inflammatory episode.

Mostpatients are children, adolescents, or adults under the age of 50.

Prolapse ofa rectal mass, rectal bleeding, constipation, diarrhea, and discomfort may bepresenting symptoms.

The lesion presents as single or multiple sessile polyps or as a cobblestoned mucosa.

The “polyps” measure from 0.5 to 5cm in diameter and have an intact mucosal surface.

Some lesions appear to result from a hypersensitivity reaction to food because the patients have high IgE levels and increased intestinal permeability.

Histologically the lesions are well circumscribed and they often have prominent germinal centers.

The lymphocytes are well differentiated without atypia or mitoses

See also

- colorecta lymphonodular hyperplasia