- Human pathology

Home > A. Molecular pathology > MUC6


Friday 23 March 2012



- MUC6 expression in pyloric gland adenoma


- Produces protective glycoprotein coat for gut epithelia
- Positive staining - normal: stomach (pyloric glands), gallbladder, colon and endocervix
- Positive staining - disease: invasive ductal carcinoma of breast, gastric carcinomas
- Negative staining: normal breast tissue


- Divergent Expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in Dysplasia and Intramucosal Adenocarcinomas With Intestinal and Foveolar Morphology: Is This Evidence of Distinct Gastric and Intestinal Pathways to Carcinogenesis in Barrett Esophagus? Khor TS, Alfaro EE, Ooi EM, Li Y, Srivastava A, Fujita H, Park Y, Kumarasinghe MP, Lauwers GY. Am J Surg Pathol. 2012 Mar;36(3):331-342. PMID: 22261707