- Human pathology

Home > D. General pathology > Vascular pathology > atherosclerosis


Saturday 22 November 2003


Digital slides

- UI:254 - Atherosclerosis - recanalization
- UI:390 - Atherosclerosis with fatty streak
- UI:614 - Atherosclerosis: Cholesterol clefts
- UI:677 - Atherosclerosis: Cholesterol clefts and dystrophic calcifiction
- UI:716: Thrombus on Atherosclerotic plaque

Definition: Atherosclerosis is a ’narrowing’ or hardening of the arteries by fibrosis of the vascular wall caused by atheroma.

Itis a pathological process that involves the progressive expansion of lesions (plaques) that reduce blood flow in arteries.

Atherosclerosis is a condition in which an artery wall thickens as a result of the accumulation of fatty materials such as cholesterol.

It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, caused largely by the accumulation of macrophage white blood cells and promoted by low-density lipoproteins (LDL, plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high-density lipoproteins (HDL), (see apoA-1 Milano).

It is commonly referred to as a hardening or furring of the arteries. It is caused by the formation of multiple plaques within the arteries.

See also

- arteriosclerosis (also known as arteriosclerotic vascular disease or ASVD)


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