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age-related EBV-associated B-cell lymphoproliferative disorders

Wednesday 28 November 2012

Age-related EBV-associated B-cell lymphoproliferative disorders; Age-related EBV-associated B-cell lymphoproliferative disease

Age-related EBV-associated lymphoproliferative disorders form a new clinicopathological group. Until recently, this group was associated with EBV-associated diffuse large B-cell lymphoma (DLBCL), characterised by an aggressive clinical presentation and a poor prognosis.


- age-related EBV-associated follicular hyperplasia
- large B-cell EBV-associaed lymphoma of the elderly


- Coexistence of age-related EBV-associated follicular hyperplasia and large B-cell EBV+ lymphoma of the elderly. Two distinct features of the same T-cell dysfunction related to senescence? Gibier JB, Bouchindhomme B, Dubois R, Hivert B, Grardel N, Copin MC. Pathol Res Pract. 2017 Mar;213(3):277-280. doi : 10.1016/j.prp.2016.12.012
PMID: 28215641

- A Case of Age-Related Epstein-Barr Virus (EBV)-Associated B Cell Lymphoproliferative Disorder, so-called Polymorphous Subtype, of the Mandible, with a Review of the Literature. Kikuchi K, Fukunaga S, Inoue H, Miyazaki Y, Kojima M, Ide F, Kusama K. Head Neck Pathol. 2012 Aug 7. PMID: 22869357#

- Age-related EBV-associated B-cell lymphoproliferative disorders: diagnostic approach to a newly recognized clinicopathological entity. Shimoyama Y, Asano N, Kojima M, Morishima S, Yamamoto K, Oyama T, Kinoshita T, Nakamura S. Pathol Int. 2009 Dec;59(12):835-43. PMID: 20021607