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extraovarian primary peritoneal carcinoma

Wednesday 24 August 2016


Definition: Extraovarian primary peritoneal carcinoma (EOPPC) develops only in women, accounts for approximately 10% of cases with a presumed diagnosis of ovarian cancer.


- FNA of extraovarian primary peritoneal carcinoma metastatic to supraclavicular lymphnode ER+ PAX8+

Characterized by abdominal carcinomatosis, uninvolved or minimally involved ovaries, and no identifiable primary, EOPPC has been reported following bilateral oophorectomy performed for benign disease or prophylaxis.

Most cases are of serous histology; however, non-serous tumors have been observed.

Although EOPPC is similar to serous ovarian carcinoma with respect to clinical presentation, histologic appearance, and response to chemotherapy, molecular and epidemiologic studies have indicated that it may be a separate entity.

Open references

- Extraovarian primary peritoneal carcinoma. Eltabbakh GH, Piver MS. Oncology (Williston Park). 1998 Jun;12(6):813-9; discussion 820, 825-6. Review.
PMID: 9644683