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low-grade dysplasia in Barrett esophagus

Tuesday 16 April 2013

Barrett Esophagus : Low-grade Dysplasia; BE



- Low grade dysplasia in Barrett esophagus resembling a tubular adenoma

Barrett esophagus is a pre-malignant condition. It is important to look for dysplasia when Barrett esophagus is diagnosed. Dysplastic changes consist of both cytologic as well as architectural atypia.

Cytologic changes include nuclear hyperchromasia and stratification, irregularly clumped chromatin, increased N:C ratios, increased mitotic activity including abnormal mitotic figures, and loss of polarity.

See also

- Vienna classification in Barrett esophagus dysplasia
- epithelial dysplasia in Barrett esophagus

Open references

- Revised British Society of Gastroenterology recommendation on the diagnosis and management of Barrett’s oesophagus with low-grade dysplasia. 2017. doi : 10.1136/gutjnl-2017-314135

- Fitzgerald RC, Di Pietro M, Ragunath K, et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett’s oesophagus. Gut 2014;63:7–42. doi : 10.1136/gutjnl-2013-305372