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Erasmus syndrome

Wednesday 15 January 2014

The silicosis is the pneumoconiosis more frequent, resulting from the inhalation of silica or silicates containing mineral dust, mainly characterized by irreversible lung fibrosis. It is associated with the development of other diseases, including pulmonary tuberculosis, lung cancer and autoimmune diseases.

The connective tissue disease after exposure to silica occurs usually after 15 years of initial exposure.The Erasmus syndrome describes the association of systemic sclerosis following exposure to silica with or without silicosis.


- Erasmus syndrome: silicosis and systemic sclerosis. de Miranda AA, Nascimento AC, Peixoto IL, Scrignoli JA, Cardoso Mdo S, Ribeiro SL. Rev Bras Reumatol. 2013 May-Jun;53(3):310-3. English, Portuguese; PMID: 24051915 [Free]