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parietal cell hyperplasia

Wednesday 10 September 2014

The oxyntic mucosa show marked hyperplasia and hypertrophy of the parietal cells. Some of these cells can be vacuolated, and many can display protrusions of apical cytoplasm into dilated oxyntic glands filled with inspissated eosinophilic material.

Etiology

- chronic omeprazole therapy (8888719)
- long-term antiacids administration
- Association achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids (15958864)
- atrophic mucosa of autoimmune gastritis