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transient acantholytic dermatosis

Tuesday 15 March 2016

Grover disease



Grover’s disease (GD) is a polymorphic, pruritic, papulovesicular dermatosis characterized histologically by acantholysis, with or without dyskeratosis.

Once confirmed, most cases of Grover’s disease last six to twelve months, which is why it was originally called "transient". However it may last much longer.

Nevertheless, it is not to be confused with relapsing linear acantholytic dermatosis.

Synopsis :

- acantholysis

  • loss of desmosomal attachment
  • acantholysis with separation of malpighian cells


- Macroscopy

- Microscopy

See also

- cutaneous diseases
-  cutaneous anomalies