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microcystic adnexal carcinoma
Wednesday 25 May 2016
MAC sclerosing sweat duct carcinoma
Definition : Microcystic adnexal carcinoma (MAC) is an uncommon cutaneous malignant neoplasm that is associated with significant morbidity in light of its propensity for local invasion. As implied by its names, MAC exhibits small keratinizing cysts and well-defined ducts.
Images
microcystic adnexal carcinoma :
- Thin bland cords and tubules. deeply infiltrative. perineural invasion.
- https://twitter.com/JMGardnerMD/status/861581982131728384
- https://twitter.com/MPLEEMD/status/1105128856959238145
Synopsis
The tumor grows very slowly over the course of years
thin bland cords & tubules : tadpoles / paisley tie pattern
keratin cysts / keratin-filled microcysts
well-defined ducts
deeply infiltrative
perineural infiltration (PNI)
biphasic malignant sweat duct tumor with ductal and follicular differentiation
bump or plaque on the upper lip, cheek or chin of older individuals
Differential diagnosis
desmoplastic trichoepithelioma
See also
- cutaneous adnexal tumors
Open references
Microcystic adnexal carcinoma in a non-Caucasian patient: A case report and review of the literature.
Chen J, Yang S, Chen J, Liao T, Deng W, Li W.
Oncol Lett. 2016 Apr;11(4):2471-2474.
PMID: 27073500 Free
