- Human pathology

Home > E. Pathology by systems > Skin > orthokeratotic Bowen disease

orthokeratotic Bowen disease

Wednesday 8 June 2016

Some examples of Bowen disease lack the characteristic broad parakeratosis making their histopathologic diagnosis particularly difficult in small and incomplete biopsies.

Orthokeratotic Bowen disease is a distinct variant of squamous cell carcinoma in situ associated with HPV infection in less than half of the cases studied (HPV-associated Bowen disease ). (26272630)

See also

- cutaneous squamous cell carcinoma in situ (Bowen disease )


- Orthokeratotic Bowen disease: a histopathologic, immunohistochemical and molecular study. Idriss MH, Misri R, Böer-Auer A. J Cutan Pathol. 2016 Jan;43(1):24-31. doi : 10.1111/cup.12610 PMID: 26272630