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direct nodal tumoral invasion

Friday 30 September 2016

direct nodal invasion

Localization

- in pulmonary carcinomas

- in pancreatic carcinomas

  • Isolated direct invasion occurs in 20% of patients with one to two positive nodes.
  • Node involvement by metastasis or by direct invasion are equally significant predictors of reduced survival. doi : 10.1007/s11605-009-1096-z
  • Both the number of positive nodes and the lymph node ratio are significant prognostic factors. doi : 10.1007/s11605-009-1096-z
  • in a 2011 study, direct lymph node invasion has similar survival to node-negative disease. (21263243)

See also

- pattern of lymph node tumoral involvement

References

- Pattern of lymph node involvement and prognosis in pancreatic adenocarcinoma: direct lymph node invasion has similar survival to node-negative disease. Pai RK, Beck AH, Mitchem J, Linehan DC, Chang DT, Norton JA, Pai RK. Am J Surg Pathol. 2011 Feb;35(2):228-34. doi : 10.1097/PAS.0b013e318206c37a
PMID: 21263243