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incipient IPMN

Wednesday 19 October 2016

incipient IPMNs

Incipient intraductal papillary mucinous neoplasms (IPMNs) are poorly described subcentimeter pancreatic cysts with papillae and mucin similar to IPMNs.

They are larger than pancreatic intraepithelial neoplasia but do not meet the cutoff size for IPMNs (≥ 1 cm).

See also : intraductal papillary mucinous neoplasm ( IPMN )

Molecular biology

- GNAS codon 201 mutations are hallmark genetic alterations of IPMNs.

See also

- incipient intraductal papillary mucinous neoplasms (IPMN )
- incipient intraductal papillary mucinous neoplasms (IPMNs )

Open references

- GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".
Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH.
Am J Surg Pathol. 2014 Mar;38(3):360-3. doi : 10.1097/PAS.0000000000000117
PMID: 24525507 Free

See also

- IPMNs / IPMN
- PanIN / PanINs