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atypical spindle cell lipomatous tumor

Friday 2 December 2016

Identification of the neoplastic adipocytic component admixed with spindle cells, and recognition of the range of histologic appearances are key for the diagnosis of atypical spindle cell lipomatous tumor.

Whereas the risk of metastatic dissemination is minimal, there is a non-negligible risk for local recurrence (13%) which warrants surgical resection with clear margins whenever feasible.

See also

- atypical adipocytic tumors with spindle cell features
- low-grade lipomatous tumors

Paywall references

- Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum.
Mariño-Enriquez A, Nascimento AF, Ligon AH, Liang C, Fletcher CD.
Am J Surg Pathol. 2017 Feb;41(2):234-244. doi : 10.1097/PAS.0000000000000770
PMID: 27879515

- Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum. Mariño-Enriquez A, Nascimento AF, Ligon AH, Liang C, Fletcher CD. Am J Surg Pathol. 2016 Nov 22. PMID: 27879515