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amphicrine carcinoma

Friday 13 July 2018

Definition: Amphicrine carcinoma is a distinct type of carcinoma characterized by synchronous exocrine and endocrine differentiation within the same tumor cell.

Such tumors are exceedingly rare and most commonly recognized in the gastrointestinal tract. In the lung, sporadic descriptions of such lesions exist.

It is a rare variant of carcinomas showing synchronous exocrine and endocrine differentiation.

Recognition of this type of tumor is important in terms of tumor classification and to identify an entity with potential aggressive behavior.

See also

- amphicrine carcinoma

Paywall references

- Pulmonary Carcinomas With Mucinous and Neuroendocrine Differentiation: Expanding the Spectrum of Amphicrine Carcinomas. Weissferdt A. Am J Surg Pathol. 2018 Jul 11. doi : 10.1097/PAS.0000000000001127 PMID: 30001241