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intramuscular granular cell tumor

Sunday 16 February 2020

Granular cell tumors (GCTs) were firstly described by Weber in 1854 and 70 years later by Abrikossoff and classified as benign tumors. Originally considered muscle tumors, they have been identified as neural lesions, due to their close association with nerve and to their immunohystochemical characteristics.

GCTs are uncommon tumors and they may arise in any part of the body; they have been mainly observed in tongue, chest wall and upper extremities; less frequent sites are larynx, gastrointestinal tract, breast, pituitary stalk and the female anogenital region.

Some cases have been described in muscle.

Open references

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573292/
- https://academic.oup.com/jscr/article/2018/2/rjy004/4837046