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penile verrucous carcinoma

Tuesday 1 March 2022


Differential diagnosis : verrucous anomalies / verrucous lesions

- giant condyloma : conspicuous koilocytosis, prominent fibrovascular cores
- hybrid verrucous carcinoma : foci of usual squamous cell carcinoma intermingled with a typical verrucous carcinoma
- papillary carcinoma : invasive and jagged border, more atypia, irregular but usually evident fibrovascular cores
- squamous hyperplasia : no atypia, no stromal reaction and no extension beyond lamina propria (in some cases distinction is not possible)
- warty carcinoma : koilocytotic change present, jagged tumor front, neoplastic cells with more pleomorphism, prominent fibrovascular cores and usually deeper invasion