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atypical urothelial cells
Friday 15 April 2022
AUC
4 cytomorphologic features in predicting HGUC :
nuclear cytoplasmic ratio
hyperchromasia
irregular nuclear membrane
coarse chromatin
Criteria for diagnosing atypical urothelial cells include one major and one minor criterion :
The major or required criterion is the presence of non-superficial and non-degenerated urothelial cells with an increased nuclear cytoplasmic (N/C) ratio (>0.5).
The minor criteria, of which only one is required, include:
- (1) mild nuclear hyperchromasia
- (2) irregular nuclear membranes (chromatinic rim or nuclear contour)
- (3) irregular, coarse, clumped chromatin.
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