- Human pathology

Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Liver > occlusion of main hepatic veins

occlusion of main hepatic veins

Tuesday 13 April 2004


- primary
- secondary

  • ulcerative colitis
  • drugs (oral contraceptives)
  • neoplasms.


Early stages

- marked dilatation in the center of the central vein
- marked dilatation of pericentral sinusoids

  • dilated sinusoids contain lysed erythrocytes

- perivenular fibrosis
- periportal regeneration with nodular changes

Late stages

- fibrosis and cirrhosis similar to liver in chronic cardiac failure

Differential diagnosis

- passive congestion (cardiac failure)