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organelle proteomics

Monday 5 July 2004

The mass-spectrometry-based identification of proteins has created opportunities for the study of organelles, transport intermediates and large subcellular structures.

Traditional cell-biology techniques are used to enrich these structures for proteomics analyses, and such analyses provide insights into the biology and functions of these structures.

See also

- organelle-associated proteins

  • mitochondrial proteins
  • basal body proteins
  • centrosomal proteins
  • endoplasmic reticulum proteins
  • Golgi-resident proteins
  • centriolar proteins
  • lysosomal proteins
  • vesicle-associated proteins
    • melanosome-associated proteins
  • sarcomeric proteins


- Yates JR 3rd, Gilchrist A, Howell KE, Bergeron JJ. Proteomics of organelles and large cellular structures. Nat Rev Mol Cell Biol. 2005 Sep;6(9):702-14. PMID: 16231421

- Pazour GJ. Comparative genomics: prediction of the ciliary and basal body proteome. Curr Biol. 2004 Jul 27;14(14):R575-7. PMID: 15268880

- Brunet S, Thibault P, Gagnon E, Kearney P, Bergeron JJ, Desjardins M. Organelle proteomics: looking at less to see more. Trends Cell Biol. 2003 Dec;13(12):629-38. PMID: 14624841