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IGFs

Monday 16 August 2004

The insulin-like growth factors (IGFs) , previosuly somatomedins, comprise a family of peptides that play important roles in mammalian growth and development.

Three main IGFs (somatomedins) have been characterized: IGF1 (somatomedin-C), IGF2 (somatomedin-A) (MIM.147470), and vitronectin (somatomedin-B) (MIM.193190).

Members

IGF1 IGF2

References

- Pollak MN, Schernhammer ES, Hankinson SE. Insulin-like growth factors and neoplasia. Nat Rev Cancer. 2004 Jul;4(7):505-18. PMID: 15229476