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epithelioid hemangioma

Tuesday 15 February 2005

Definition: Epithelioid hemangioma is an uncommon vascular tumefaction of uncertain pathogenesis.

Digital cases

- Case 162 (HPC:162) : Epithelioid hemangioma of bones (Hand)

Images

- Epithelioid hemangioma

The anatomic sites most frequently affected by epithelioid hemangioma are the head (in the distribution of the superficial temporal artery) and the distal portions of the extremities, especially the digits.

Localization

- soft tissue epithelioid hemangioma
- penile epithelioid hemangioma (15087672)
- epithelioid hemangioma of bones

Microscopy

- proliferation of epithelioid endothelial cells
- nodular or lobular configuration
- inflammatory infiltrate containing lymphocytes and eosinophils
- associated with a small arterial segment

  • mural damage
  • intraluminal epithelioid endothelial cells

Molecular biology

- Frequent FOS Gene Rearrangements in epithelioid hemangioma (26135557)

See also

- Vascular tumors

  • epithelioid vascular tumors

References

- Epithelioid hemangioma of bone revisited: a study of 50 cases. Nielsen GP, Srivastava A, Kattapuram S, Deshpande V, O’Connell JX, Mangham CD, Rosenberg AE. Am J Surg Pathol. 2009 Feb;33(2):270-7. PMID: 18852673

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