Home > E. Pathology by systems > Skin > atopic dermatitis
atopic dermatitis
Thursday 12 May 2005
Susceptibility SNPs
rs479844 upstream of OVOL1
rs2164983 near ACTL9 (proliferation and differentiation)
rs2897442 in KIF3A within the cytokine cluster at 5q31.1
FLG locus
11q13.5
20q13.33
Reviews
Williams HC. Clinical practice. Atopic dermatitis. N Engl J Med. 2005 Jun 2;352(22):2314-24. PMID: 15930422
Bowcock AM, Cookson WO. The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum Mol Genet. 2004 Apr 1;13 Spec No 1:R43-55. PMID: 14996755
Galli E, Cicconi R, Rossi P, Casati A, Brunetti E, Mancino G. Atopic dermatitis: molecular mechanisms, clinical aspects and new therapeutical approaches. Curr Mol Med. 2003 Mar;3(2):127-38. PMID: 12630559
References
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Paternoster L, Standl M, Chen CM et al. Nat Genet. 2011 Dec 25. PMID: 22197932
